ELK Biotechnology Adenosine A3-R rabbit pAb
Adenosine A3-R rabbit polyclonal antibody for WB, IF, ELISA. Recognizes human ADORA3 receptor involved in cardioprotection and neuroregulation. High specificity and stability with -20°C storage for 1 year.
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Adenosine A3-R rabbit pAb
Supplier: ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Adenosine A3-R rabbit pAb |
| Alternative Names | ADORA3; Adenosine receptor A3 |
| Applications | WB; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ADORA3 (AA range: 255–304) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 36 kD |
| GeneID (Human) | 140 |
| Human Swiss-Prot No | P33765 |
| Cellular Localization | Plasma membrane; integral component of membrane |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a protein belonging to the family of adenosine receptors, which are G-protein-coupled receptors involved in various intracellular signaling pathways and physiological functions. The receptor mediates a sustained cardioprotective function during cardiac ischemia, inhibits neutrophil degranulation in tissue injury, and is implicated in both neuroprotective and neurodegenerative processes. It may also regulate cell proliferation and death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with transcripts from overlapping GeneID:57413, encoding an immunoglobulin domain-containing protein. (RefSeq, Nov 2014)
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