ELK Biotechnology Histone H4 (Acetyl Lys12) rabbit pAb
Histone H4 (Acetyl Lys12) 특이 토끼 폴리클로날 항체로, 아세틸화된 H4K12 부위를 인식합니다. WB, IHC, IF, ELISA에 사용 가능하며 인간, 마우스, 랫, 원숭이에 반응합니다. 고순도 IgG 형태로 안정적 보관이 가능합니다.
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Histone H4 (Acetyl Lys12) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H4 (Acetyl Lys12) rabbit pAb |
| Alternative Names | HIST1H4A; H4/A; H4FA; HIST1H4B; H4/I; H4FI; HIST1H4C; H4/G; H4FG; HIST1H4D; H4/B; H4FB; HIST1H4E; H4/J; H4FJ; HIST1H4F; H4/C; H4FC; HIST1H4H; H4/H; H4FH; HIST1H4I; H4/M; H4FM; HIST1H4J; H4/E; H4FE; HIST1H4K; H4/D; H4FD; HIST1H4L; H4/K; H4FK; H4K12AC |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 Immunofluorescence: 1/200–1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Histone H4 around the acetylated site of Lys12 (AA range: 10–59) |
| Host | Rabbit |
| Storage | −20 °C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 11 kDa |
| GeneID (Human) | 121504 / 554313 / 8294 / 8359 / 8360 / 8361 / 8362 / 8363 / 8364 / 8365 / 8366 / 8367 / 8368 / 8370 |
| Human Swiss-Prot No | P62805 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat, Monkey |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures.
This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but contain a palindromic termination element. The gene is located in the histone microcluster on chromosome 6p21.33 (RefSeq, Aug 2015).
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