ELK Biotechnology SCG10 (phospho Ser73) rabbit pAb
SCG10 (phospho Ser73) rabbit pAb은 신경 성장 및 미세소관 동역학 연구에 적합한 인산화 특이 항체입니다. 인간, 마우스, 랫트에 반응하며 IHC, IF, ELISA에 사용 가능합니다. 고순도 IgG 폴리클로날 항체로 -20°C에서 1년 보관 가능합니다.
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제품명
SCG10 (phospho Ser73) rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | STMN2; SCG10; SCGN10; Stathmin-2; Superior cervical ganglion-10 protein; Protein SCG10 |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human SCG10 (phospho Ser73) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 11075 |
| Human Swiss-Prot No | Q93045 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Cytoplasm; perinuclear region; growth cone; membrane (peripheral, cytoplasmic side); axon; Golgi apparatus; endosome; lamellipodium. Associated with punctate structures in perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms. Colocalized with CIB1 in neurites, cell body, and growth cones of neurons; also at the leading edge of lamellipodia. |
Background
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. (Provided by RefSeq, Nov 2010)
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