Thermo Fisher Scientific PPAR alpha Polyclonal Antibody
PPAR alpha 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 사용 가능. 인간 PPARα의 아미노산 25 주변 합성 펩타이드로부터 제작됨. 약 52 kDa 밴드 검출. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–4 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide surrounding amino acid 25 of human PPARα |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_1959487 |
Product Specific Information
- Detects a band of approximately 52 kDa.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Peroxisome proliferators are non-genotoxic carcinogens that exert their effects through interaction with nuclear hormone receptors known as peroxisome proliferator activated receptors (PPARs).
These ligand-dependent intracellular proteins stimulate transcription of specific genes by binding to DNA sequences following activation by appropriate ligands.
PPARs are activated by compounds such as clofibric acid, nafenopin, WY-14,643, and certain fatty acids.
They can induce transcription of acyl coenzyme A oxidase and cytochrome P450 (CYP450) A6 through interaction with response elements.
PPARs also heterodimerize with retinoid X receptor (RXR) alpha.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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