ELK Biotechnology Lefty rabbit pAb
Lefty rabbit polyclonal antibody for detection of LEFTY1/LEFTY2 proteins in human and mouse samples. Suitable for WB and IHC applications with high specificity. Targets C-terminal peptide region. Stable at -20°C for up to 1 year.
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제품명
Lefty rabbit pAb
공급업체
ELK Biotechnology
제품 설명
Lefty rabbit polyclonal antibody는 인간 LEFTY1 및 LEFTY2 단백질의 C-말단 영역을 인식하도록 제작된 항체입니다. TGF-beta 슈퍼패밀리 단백질의 리간드로서, 기관계의 좌우 비대칭성 결정에 관여하는 LEFTY 단백질 검출에 사용됩니다.
스펙 정보
| 항목 | 내용 |
|---|---|
| Product name | Lefty rabbit pAb |
| Alternative Names | LEFTY1; LEFTB; LEFTYB; Left-right determination factor 1; Left-right determination factor B; Protein lefty-1; Protein lefty-B; LEFTY2; EBAF; LEFTA; LEFTYA; TGFB4; PSEC0024; Left-right determination factor 2; Endometrial bleeding-associated factor; Left-right determination factor A; Protein lefty-2; Protein lefty-A; Transforming growth factor beta-4; TGF-beta-4 |
| Applications | WB; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300 |
| Immunogen | Synthesized peptide derived from the C-terminal region of human LEFTY1/LEFTY2 (AA range: 301–350) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 40 kD |
| GeneID (Human) | 10637 / 7044 |
| Human Swiss-Prot No | O75610 / O00292 |
| Cellular Localization | Secreted |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene. (RefSeq, Aug 2016)
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