ELK Biotechnology GDF-3 rabbit pAb
GDF-3 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. TGF-β 신호전달 관련 연구에 활용 가능하며, 인간·쥐·마우스 시료에 반응합니다. -20°C에서 1년간 안정적으로 보관됩니다.
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제품명
GDF-3 rabbit pAb
대체 명칭
GDF3; Growth/differentiation factor 3; GDF-3
제품 응용
- WB
- ELISA
권장 희석 배수
- Western Blot: 1/500 - 1/2000
- ELISA: 1/10000
- 기타 응용은 아직 테스트되지 않음
제품 정보
| 항목 | 내용 |
|---|---|
| Immunogen | Synthesized peptide derived from Growth/differentiation factor 3 (AA range: 311–360) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 41 kD |
| GeneID (Human) | 9573 |
| Human Swiss-Prot No | Q9NR23 |
| Cellular Localization | Secreted; Cytoplasm; Mainly accumulated in the cytoplasm |
| Species Reactivity | Human; Rat; Mouse |
배경 (Background)
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients.
[provided by RefSeq, Aug 2016]
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