ELK Biotechnology CD36 rabbit pAb
CD36 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, ELISA에 사용 가능. 세포막 단백질 검출에 적합하며, 인간, 마우스, 랫트, 틸라피아 시료에 반응. 합성 펩타이드 면역원으로 제작되어 높은 특이성과 신뢰성 제공.
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제품명
CD36 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | CD36; GP3B; GP4; Platelet glycoprotein 4; Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV; GPIV; Thrombospondin receptor; CD36 |
| Applications | WB; IHC; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/10000 Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from the internal region of human CD36 (AA range: 331–380) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 90 kDa |
| Gene ID (Human) | 948 |
| Human Swiss-Prot No. | P16671 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein; Membrane raft; Golgi apparatus; Apical cell membrane. Upon ligand-binding, internalized through dynamin-dependent endocytosis. |
| Species Reactivity | Human; Mouse; Rat; Tilapia |
Background
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids, and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and binds long-chain fatty acids, functioning in their transport and/or regulation. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been identified for this gene (RefSeq, Feb 2014).
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