
Thermo Fisher Scientific HLA-A2 Monoclonal Antibody (BB7.2), Alexa Fluor 647
인간 HLA-A2 항원을 인식하는 mouse monoclonal antibody (clone BB7.2)로, Alexa Fluor 647 형광 표지되어 있습니다. Flow cytometry에 적합하며, 650/671 nm의 발광 특성을 가집니다. PBS와 BSA buffer에 보관하며, 연구용으로 사용됩니다.
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Applications
- Flow Cytometry (Flow): 5 µL per 100 µL whole blood or 10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BB7.2 |
| Immunogen | HLA-A2 solubilised by papain |
| Conjugate | Alexa Fluor™ 647 |
| Excitation / Emission Max | 650 / 671 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898660 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope at the C-terminus of the alpha-2 helix and a turn on one of the underlying beta strands within the human HLA-A2 histocompatibility antigen.
Target Information
HLA-A is part of the HLA class I heavy chain family. It forms a heterodimer with beta-2 microglobulin and is anchored in the membrane. Class I molecules present peptides from the endoplasmic reticulum lumen and are expressed in nearly all cells. The heavy chain (~45 kDa) gene contains 8 exons, encoding leader, alpha domains, transmembrane, and cytoplasmic regions. Polymorphisms in exons 2 and 3 determine peptide binding specificity, critical for transplantation typing.
HLA and MHC antibodies are essential in Immunopeptidomics for identifying and characterizing neoantigens via LC-MS/MS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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