Thermo Fisher Scientific GABRG1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 200-260 of human GABRG1 (NP_7758072) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GABRG1,uniProtId:Q8N1C3-1,ncbiNodeId:9606,antigenRange:200-260,antigenLength:465,antigenImageFileName:PA5-89695_GABRG1_Q8N1C3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89695_GABRG1_Q8N1C3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.36 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805730

Product Specific Information

Immunogen sequence: HSCPLEFSSY GYPKNEIEYK WKKPSVEVAD PKYWRLYQFA FVGLRNSTEI THTISGDYVI M; Positive Samples: U-87MG, Mouse brain; Cellular Location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse

Target Information

Gabrg1 encodes a protein that belongs to the ligand-gated ionic channel family. Gabrg1 is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. The Gabrg1 gene is clustered with three other family members on chromosome 4. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels and, along with GABAB receptors, are responsible for mediating the inhibitory effects of GABA. Structurally, Gabrg1 are pentameric proteins, consisting of five subunits belonging to different families. Diseases associated with GABRG1 include Alcohol Dependence.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.