Thermo Fisher Scientific GABRG1 Polyclonal Antibody
Rabbit polyclonal antibody targeting GABRG1 for WB, ICC/IF, and ELISA applications. Recognizes human, mouse, and rat. Supplied as a liquid, affinity-purified, unconjugated antibody. Suitable for detecting GABAA receptor gamma subunit 1 in research stud...
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- PA589695
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 200–260 of human GABRG1 (NP_7758072) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.36 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805730 |
Product Specific Information
- Immunogen sequence: HSCPLEFSSY GYPKNEIEYK WKKPSVEVAD PKYWRLYQFA FVGLRNSTEI THTISGDYVI M
- Positive samples: U-87MG, Mouse brain
- Cellular location: Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Target Information
Gabrg1 encodes a protein of the ligand-gated ionic channel family. It is an integral membrane protein that plays a key role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. The Gabrg1 gene is located on chromosome 4, clustered with other family members.
GABAA receptors belong to the Cys-loop ligand-gated ion channel family and mediate inhibitory effects of GABA. Structurally, Gabrg1 forms pentameric complexes composed of five different subunits.
Diseases associated with GABRG1 include Alcohol Dependence.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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