Thermo Fisher Scientific MKL1 Monoclonal Antibody (OTI2G6), TrueMAB
MKL1 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. Human 시료에 반응하며, 무보존제 동결건조 형태로 제공됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 165–397 of human MKL1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The MKL1 protein interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. It is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus.
This gene is involved in a translocation event creating a fusion with the RNA-binding motif protein-15 gene, associated with acute megakaryocytic leukemia.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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