Thermo Fisher Scientific ETFA Polyclonal Antibody
ETFA 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. 인간, 마우스, 랫트 반응성 확인. Western blot에 최적화된 항체로 고순도 정제 및 안정적 액상 형태 제공. 연구용으로 미토콘드리아 지방산 β-산화 관련 연구에 적합.
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Applications
- Western Blot (WB): 0.05–0.2 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QVADYGIVADLFK) corresponding to the C-terminus amino acids of ETFA (aa 309–321) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10983341 |
Product Specific Information
- Predicted to react with bovine and canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
ETFA participates in catalyzing the initial step of mitochondrial fatty acid β-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase.
Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria, where multiple acyl-CoA dehydrogenase deficiencies result in excess excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.
Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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