Thermo Fisher Scientific mGluR2 Monoclonal Antibody (6E4F6)
mGluR2 단백질을 인식하는 Mouse monoclonal 항체로, Western blot, Flow cytometry, ELISA 등에 사용 가능. Human 시료 반응성. Protein G 정제, PBS buffer(0.05% sodium azide) 용액 형태. 단기 4°C, 장기 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6E4F6 |
| Immunogen | Purified recombinant fragment of human GRM2 (AA: extra 414–558) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090952 |
Target Information
Glutamate is the main excitatory neurotransmitter in the brain. It acts on ligand-gated receptor channels such as NMDA, AMPA, and kainate receptors involved in fast excitatory synaptic transmission. Additionally, glutamate regulates enzymes producing second messengers via G-protein-coupled metabotropic glutamate receptors (mGluRs).
Group I receptors (mGluR1a, mGluR5) stimulate phospholipase C, while Group II and III receptors (mGluR2, mGluR3) inhibit adenylyl cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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