Thermo Fisher Scientific Human RHBDD1 Synthetic Peptide
인간 RHBDD1 단백질의 C-말단 14개 아미노산 서열에 해당하는 합성 펩타이드입니다. PA5-20860 항체의 블로킹 펩타이드로 사용 가능합니다. 세포자멸사 연구 및 생식세포 분화 관련 연구에 활용됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PEP0974
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the carboxy terminus of human RHBDD1.
PEP-0974 can be used as a blocking peptide with polyclonal antibody PA5-20860.
Target Information
The Rhomboid family of proteins is composed of widely conserved polytopic membrane serine proteases involved in growth and development. RHBDD1 is highly expressed in the testis and plays a role in the cleavage of BIK, a proapoptotic member of the Bcl-2 family.
Overexpression or suppression of RHBDD1 in 293 cells affects BIK-mediated apoptosis, indicating that RHBDD1 modulates apoptotic activity.
In GC-1 spermatogonia cells, suppression of RHBDD1 expression by RNAi leads to loss of survival and differentiation ability in mouse seminiferous tubules, suggesting its role in mammalian spermatogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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