Thermo Fisher Scientific PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Recombinant Rabbit Monoclonal Antibody (PDL1/7568R)
PD-L1 단백질을 표적하는 재조합 토끼 단클론 항체로, 암 면역치료 연구용으로 적합. 인간 시료에 반응하며 IHC(P) 및 IHC(PFA) 실험에 사용 가능. 고순도 Protein A/G 정제, 액상 형태로 제공. 4°C 보관, 동결 금지.
- 카탈로그번호
- 29126-RBM18-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Recombinant Rabbit Monoclonal Antibody (PDL1/7568R)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PDL1/7568R |
| Immunogen | Recombinant fragment (around aa190–290) of human CD274 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. PD-L1 binds to its receptor PD-1, which negatively regulates T-cell receptor (TCR) signaling. Upon receptor binding, PD-L1 reduces TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in various murine and human cancers and can be up-regulated by IFN-γ stimulation. Therefore, PD-L1 may play a critical role in tumor immune evasion.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: 29126-RBM18-P0_PD-L1_CD274_Q9NZQ7-1_Rabbit.svg, 29126-RBM18-P0_PD-L1_CD274_Q9NZQ7-1_Rabbit_PDP.jpeg)
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