Thermo Fisher Scientific Profilin 1 Polyclonal Antibody
Rabbit polyclonal antibody against human Profilin 1, validated for WB and ICC/IF. Affinity purified and supplied as liquid in PBS with glycerol and BSA. Suitable for research use only; reactive with human and non-human primates.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PFN1 (aa 1–140) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 30% glycerol, 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609640 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with specific proteins or peptides. The antibodies are affinity purified from rabbit sera and tested for functionality in various research applications. Developed for Research Use Only, these antibodies are non-hazardous and non-infectious.
This antibody is predicted to react with Monkey, Rat, Mouse, Pig, and Bovine.
Target Information
Profilin is a ubiquitous small (12–15 kDa) phosphoinositide and poly-L-proline binding protein involved in signal transduction and actin filament dynamics. There are two mammalian profilins with similar biochemical properties but distinct expression patterns:
- Profilin I: Highly expressed in most tissues except skeletal muscle
- Profilin II: Predominantly expressed in brain, with lower levels in skeletal muscle, uterus, and kidney
Profilin is mainly cytosolic and enriched in dynamic membrane regions such as the leading edge and ruffling membranes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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