Thermo Fisher Scientific IARS Polyclonal Antibody
Rabbit polyclonal antibody targeting human IARS (Isoleucyl-tRNA Synthetase). Validated for WB and IP applications. Supplied as unconjugated liquid form at 1 mg/mL concentration. Recommended storage at 4°C with 1-year shelf life. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 to 50 of human Isoleucyl-tRNA Synthetase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
IARS (Isoleucyl-tRNA Synthetase) is a member of aminoacyl-tRNA synthetases that catalyze the aminoacylation of tRNA by their cognate amino acid. These enzymes play a central role in linking amino acids with nucleotide triplets contained in tRNAs and are considered among the earliest proteins in evolution.
Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5′ UTRs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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