Thermo Fisher Scientific XRCC1 Monoclonal Antibody (OTI2D8), TrueMAB
XRCC1 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot, IHC, Flow Cytometry에 적합. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제, 동결건조 형태로 안정적 보관 가능. DNA 손상 복구 연구에 활용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D8 |
| Immunogen | Full length human recombinant protein of human XRCC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. It is a 70 kDa protein associated with DNA repair enzymes including poly (ADP-ribose) polymerase (PARP), DNA Ligase III, and DNA polymerase beta.
XRCC1 contains a BRCT domain, originally identified in BRCA1, which mediates protein-protein interactions with DNA ligase III-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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