Thermo Fisher Scientific CUEDC1 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal CUEDC1 항체. Western Blot 및 IHC에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공. 단기 2–8°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide near the carboxy terminus of human CUEDC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155207 |
Product Specific Information
- Suggested positive control: rat liver tissue lysate
- PA5-20619 can be used with blocking peptide PEP-0739.
Target Information
The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, approximately 40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation.
CUE domains are present in eukaryotic proteins involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found.
CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways. Two isoforms of CUEDC1 exist due to alternative splicing events.
Defects in the CUEDC1 gene may be associated with early-stage cervical cancer, implicating CUEDC1 as a potential tumor marker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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