Thermo Fisher Scientific PSAP Polyclonal Antibody
Human PSAP 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 40% 글리세롤 버퍼에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PSAP (Product # RP-102428) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789314 |
Product Specific Information
Immunogen sequence:
TNSTFVQALV EHVKEECDRL GPGMADICKN YISQYSEIAI QMMMHMQPKE ICALVGFCDE VKEMPMQTLV PAKVASKNVI PALELVEPIK KHEVPAKSDV YCEVCEFLVK EVTKLIDNNK TEKEILDAFD KMCSKLPKSL SEE
Target Information
PSAP is a highly conserved glycoprotein that serves as a precursor for four cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acids long and shares similar cysteine residue and glycosylation site placement.
Saposins A–D primarily localize to the lysosomal compartment, facilitating the catabolism of glycosphingolipids with short oligosaccharide groups.
The precursor protein exists both as a secretory and an integral membrane protein and exhibits neurotrophic activities.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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