Thermo Fisher Scientific CD13 Polyclonal Antibody
CD13 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 적합합니다. 인간 시료 반응성이 있으며, 항원 친화 크로마토그래피로 정제된 액상형 제품입니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ANPEP. Recombinant protein control fragment (Product #RP-102251). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789317 |
Product Specific Information
Immunogen sequence:
PNTLKPDSYR VTLRPYLTPN DRGLYVFKGS STVRFTCKEA TDVIIIHSKK LNYTLSQGHR VVLRGVGGSQ PPDIDKTELV EPTEYLVVHL KGSLVKDSQY EMDSEFEGEL ADDLAGFYRS EYMEGNVRKV VATTQMQA
Target Information
CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types.
It catalyzes removal of neutral amino acids from small peptides, activating or inactivating bioactive peptides.
CD13 participates in extracellular matrix degradation, antigen processing, and signal transduction.
It is involved in inflammatory responses, regulates intercellular contact, cell motility, and vascularization.
CD13 is expressed by granulocytes, monocytes, and myeloid leukemia cells, and its expression correlates with poor prognosis in carcinomas.
CD13 also functions as an aminopeptidase enzyme and serves as an alpha receptor for coronavirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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