Thermo Fisher Scientific LRP1 Polyclonal Antibody
Human LRP1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보관됩니다. 알츠하이머 관련 연구 등 세포 신호전달 및 지질 항상성 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LRP1. Recombinant protein control fragment (Product # RP-102330) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789303 |
Product Specific Information
Immunogen sequence:
STCTVNQGNQ PQCRCLPGFL GDRCQYRQCS GYCENFGTCQ MAADGSRQCR CTAYFEGSRC EVNKCSRCLE GACVVNKQSG DVTCNCTDGR VAPSCLTCVG HCSNGGSCTM NSKMMPECQC PPHMTGPRCE EHVF
Target Information
The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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