Thermo Fisher Scientific GTF3A Polyclonal Antibody
Rabbit polyclonal antibody targeting human GTF3A protein. Validated for IHC and ICC/IF applications. Recombinant immunogen-based design ensures high specificity. Suitable for research use only; store at 4°C short term or -20°C long term.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:20–1:50
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GTF3A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Lot-Specific |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642259 |
Product Specific Information
Immunogen sequence:
KRKDYLKQHM KTHAPERDVC RCPREGCGRT YTTVFNLQSH ILSFHEESRP FVCEHAGCGK TFAMKQSLTR HAVVHDPDKK KMKLKVKKSR EKRSLASHLS GYIPPKRKQG QGLSLCQNGE SPNCVEDKML STV
- Highest antigen sequence identity to the following orthologs:
- Mouse: 74%
- Rat: 77%
Target Information
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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