Thermo Fisher Scientific ENY2 Monoclonal Antibody (GT245)
ENY2 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot, IHC, ICC/IF에 사용 가능. 인간 및 랫트 반응성 확인, 다양한 종에 예측 반응성 있음. PBS 용액 형태로 보존제 무첨가, 장기 보관 시 -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT245 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ENY2 (proprietary sequence) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2735176 |
Product Specific Information
- Positive Control: U87-MG, SK-N-SH, IMR32
- Predicted Reactivity: Mouse (100%), Zebrafish (85%), Xenopus laevis (93%), Pig (100%), Chicken (96%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ENY2 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ENY2 participates in a subcomplex that specifically deubiquitinates histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. ENY2 is also required for nuclear receptor-mediated transactivation and may participate in mRNA export and chromatin positioning by tethering genes to the nuclear periphery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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