
Thermo Fisher Scientific DDX3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human DDX3 protein. Validated for Western blot and immunoprecipitation. Unconjugated, liquid form, 1 mg/mL concentration. Predicted cross-reactivity with mouse, orangutan, and chimpanzee. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:5,000–1:15,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 600 and the C-terminus (residue 661) of human DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Orangutan, and Chimpanzee
Target Information
The protein encoded by this gene is a member of the large DEAD-box protein family, characterized by the conserved Asp-Glu-Ala-Asp (DEAD) motif and ATP-dependent RNA helicase activity. It exhibits high RNA-independent ATPase activity and is stimulated by both RNA and DNA.
This protein functions in both nucleus and cytoplasm, participating in:
- Transcriptional regulation
- mRNP assembly
- Pre-mRNA splicing
- mRNA export
- Translation, cellular signaling, and viral replication
Misregulation of this gene has been implicated in tumorigenesis. A paralog exists on the Y chromosome, and pseudogenes are found on chromosomes 4 and X. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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