
Thermo Fisher Scientific Phospho-PKC epsilon (Ser729) Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000
View 4 publications 4 publications
Immunohistochemistry (Frozen) (IHC (F))
-
View 1 publication 1 publication
Product Specifications
Species Reactivity
Human, Mouse
Published species
Human, Virus
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human PKCe that contains serine 729. The sequence is conserved in mouse and rat. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
PKC epsilon,
uniProtId:
Q02156-1,
ncbiNodeId:
9606,
antigenRange:
729,
antigenLength:
737,
antigenImageFileName:
44-977G_PKC_epsilon_Q02156-1_Rabbit.svg,
antigenImageFileNamePDP:
44-977G_PKC_epsilon_Q02156-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco`s PBS, pH 7.3, with 1mg/mL BSA
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2533816
Target Information
The PKC family of serine/threonine kinases, including PRKCE (PKC epsilon), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. Protein kinase C (PKC) can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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