Thermo Fisher Scientific Phospho-PKC delta (Ser664) Polyclonal Antibody
PKC delta 단백질의 Ser664 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, -20°C에서 보관. 인간 및 랫트 시료에 반응함.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Chemically synthesized phosphopeptide derived from a region of human PKC delta containing serine 664 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.3, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533815 |
Target Information
The PKC family of serine/threonine kinases, including PRKCD (PKC delta), is activated by intracellular signal transduction pathways. In humans, at least 12 PKC isoforms have been identified, differing in structure, tissue distribution, localization, and substrate specificity. Conventional PKC isoforms (alpha, beta I, beta II, gamma) are Ca²⁺ and phospholipid-dependent.
PKC family members phosphorylate a wide range of protein targets and play key roles in cellular signaling pathways. They also act as receptors for phorbol esters, known tumor promoters. PKC delta is involved in B cell signaling, growth regulation, apoptosis, and differentiation across various cell types. Alternatively spliced transcript variants encoding the same protein have been observed in human and mouse studies.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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