Thermo Fisher Scientific Phospho-Caspase 6 (Ser257) Polyclonal Antibody
Phospho-Caspase 6 (Ser257)에 특이적인 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 사용 가능. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 인간, 마우스, 랫트 반응성. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human Caspase 6 around the phosphorylation site of Ser257 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Caspases are cysteine proteases expressed as inactive precursors that mediate apoptosis by proteolysis of specific substrates. They cleave after aspartic acid residues and are divided into initiator caspases (activated by receptor clustering) and effector caspases (activated by mitochondrial permeability transition). Initiator caspases such as Caspase-8 and Caspase-9 activate effector caspases like Caspase-3 and Caspase-7, leading to cell collapse.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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