Thermo Fisher Scientific CD98 Monoclonal Antibody (MEM-108), PE
CD98 단백질에 특이적으로 결합하는 단클론 항체로, 인체 시료에 반응합니다. PE 형광표지로 유세포분석(Flow Cytometry)에 최적화되어 있습니다. 액상 형태로 제공되며, 안정적인 보관을 위해 4°C 암소에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution
- 20 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-108 |
| Immunogen | RAJI human Burkitt's lymphoma cell line |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2534551 |
Additional Formats
- Unconjugated (MA1-19195)
- Biotin (MA1-19509)
- FITC (MA1-19586)
- Custom conjugation available upon request
Product Specific Information
This antibody reacts with an extracellular epitope of CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glycosylated light chain).
CD98 is expressed on T lymphocytes (upon activation) and activated NK cells; it is also present at low levels on B lymphocytes, NK cells, monocytes, and platelets.
Target Information
CD98 (4F2) is a type II transmembrane glycoprotein that serves as the heavy chain of heterodimeric amino acid transporters (HATs).
Linked to various light chains by disulfide bonds, CD98 is responsible for cell surface expression and basolateral localization of the transporter complex in polarized epithelial cells.
It also interacts with beta1 integrins, increasing their ligand affinity.
Beyond amino acid transport, CD98 is involved in cell fusion, activation, and regulation of differentiation, growth, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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