Thermo Fisher Scientific CD147 Monoclonal Antibody (MEM-M6/1), PE

Applications

• Flow Cytometry (Flow): 20 µL / 1×10⁶ cells

Product Specifications

Additional Formats

• Unconjugated (MA1-19201)
• Alexa Fluor 488 (MA5-18126)
• APC (MA1-10104)
• Biotin (MA1-19511)
• FITC (MA1-19588)
• Custom conjugation available upon request

Product Specific Information

This antibody recognizes an extracellular epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50–60 kDa type I transmembrane glycoprotein primarily expressed on leukocytes, red blood cells, platelets, and endothelial cells, but not on resting lymphocytes.
The MEM-M6/1 clone exhibits high affinity and is capable of binding to unstimulated peripheral blood T cells.

Target Information

CD147 (also known as basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50–60 kDa glycoprotein with multiple glycosylated forms.
It is a plasma membrane protein involved in spermatogenesis, embryo implantation, neural network formation, and tumor progression, and belongs to the immunoglobulin superfamily.
High expression is observed in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
CD147 facilitates cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulates integrin functions, and plays roles in cell development, activation, fetal development, and retinal function.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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