Thermo Fisher Scientific FLIP Polyclonal Antibody
FLIP 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF에 적합. 인간 FLIP2 아미노산 서열(2–18)에 대응하는 펩타이드로 면역화. 세포 생존 및 사멸 경로 연구에 유용하며, 비결합형 액상 형태로 제공.
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Thermo Fisher Scientific FLIP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to amino acids 2–18 of human FLIP2. The sequence is identical in all FLIP splice variants. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2080771 |
Product Specific Information
The PA1-30801 immunogen is a peptide corresponding to amino acids 2–18 of human FLIP2. The sequence is identical in all FLIP splice variants.
Target Information
FLIP (CFLAR) is an apoptosis regulator protein that functions as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6-mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC), thereby blocking further recruitment and processing of caspase-8 at the complex. Full-length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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