Thermo Fisher Scientific Phospho-MAPKAPK2 (Thr222) Polyclonal Antibody
MAPKAPK2의 Thr222 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 1 mg/mL 농도의 액상형 제품으로 -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MAPKAPK2 (Accession P49137), corresponding to amino acid residues around phosphorylated Thr222 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816085 |
Product Specific Information
This antibody detects endogenous levels of MAPKAPK2 only when phosphorylated at Thr222.
Target Information
MAPKAPK2 mediates p38 and ERK signaling in vivo and is involved in various cellular processes such as stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation. It encodes a member of the Ser/Thr protein kinase family and is regulated through direct phosphorylation by p38 MAP kinase. Heat shock protein HSP27 is one of its known substrates. Two transcript variants encoding different isoforms have been identified for MAPKAPK2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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