
Thermo Fisher Scientific MMP24 Polyclonal Antibody
MMP24 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 Immunocytochemistry에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MMP24 (Accession Q9Y5R2), corresponding to amino acid residues F442–K492. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2815732 |
Product Specific Information
Antibody detects endogenous levels of total MMP24.
Target Information
All cells within tissues are surrounded by an extracellular matrix (ECM) giving the tissues shape and structure. The ECM is constantly being remodeled and constant communication is maintained between cells through this matrix. Secreted proteins, termed matrix metalloproteinases (MMPs), are involved in the modulation of cell-matrix interactions.
MMPs are Zn(2+)-binding endopeptidases that degrade various components of the ECM. They play key roles in normal and pathological tissue remodeling, wound healing, angiogenesis, and tumor invasion. These enzymes are highly potent when active and are regulated by extracellular inhibitors known as TIMPs (tissue inhibitors of matrix metalloproteinases). TIMPs can block tumor cell invasion and act as metastasis suppressor genes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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