Thermo Fisher Scientific CCRL2 Polyclonal Antibody

Applications

• Western Blot (WB): 1:500–1:3,000

Product Specifications

Product Specific Information

• Recommended positive controls: NIH-3T3, THP-1
• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

CCRL2 (C-C chemokine receptor-like 2), also known as chemokine receptor X, human chemokine receptor (HCR), CRAM-A or CRAM-B, is a seven-pass transmembrane protein expressed by monocytes, neutrophils, and dendritic cells of immune tissues (predominantly spleen, fetal liver, bone marrow, and lymph node).
It shares over 40% homology with other C-C chemokine receptors but lacks the conserved DRY motif necessary for signaling and ligand-binding.
C-C chemokine receptors are G-protein-coupled, seven-pass transmembrane domain proteins whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to areas of inflammation.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.