Thermo Fisher Scientific SAPK4 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1368)
Recombinant alpaca monoclonal antibody against human MAPK13 (p38 delta). Suitable for ICC/IF, ELISA, and IP assays. Expressed in CHO cells and purified by metal-chelate chromatography. Provided as liquid form, 1 mg/mL concentration, ideal for research ...
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1368 |
| Immunogen | Recombinant Human MAPK13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase that transduces various extracellular signals, including cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by environmental stresses and proinflammatory cytokines. Activation occurs through phosphorylation by MAP kinase kinases or autophosphorylation triggered by MAP3K7IP1/TAB1 interaction. Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, indicating roles in stress-related transcription, cell cycle regulation, and genotoxic stress response. Four alternatively spliced transcript variants of SAPK4 encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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