Thermo Fisher Scientific ARTS Polyclonal Antibody
Western blot, IHC, ICC/IF에 사용 가능한 ARTS 단클론 항체로 인간, 마우스, 랫트 반응성이 있습니다. Rabbit IgG 폴리클로날 항체이며, 합성 펩타이드 항원으로 제작되었습니다. PBS/50% 글리세롤에 보관하며 -20°C에서 안정적입니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SEPT4 (Accession O43236), corresponding to amino acid residues S86–R136 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900516 |
Product Specific Information
This antibody detects endogenous levels of total SEPT4.
Target Information
Apoptosis is related to many diseases and developmental processes. Mitochondrial proteins such as cytochrome c, Apaf-1, and AIF play important roles in apoptosis. A novel mitochondrial septin-like protein, designated ARTS (Apoptosis Related protein in TGF-beta Signaling pathway), has been identified.
ARTS, encoded by the human septin H5/PNUTL2/CDCrel2b gene, localizes to mitochondria and translocates to the nucleus during apoptosis. It is expressed in many tissues and enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents such as TNF-α and Fas ligand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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