Thermo Fisher Scientific EHHADH Polyclonal Antibody
EHHADH 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 사용 가능. 인간 EHHADH 아미노산 444-723 서열 기반 면역원 사용. Peroxisome 위치 단백질 검출에 적합하며, 연구용으로 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 444–723 of human EHHADH (NP_001957.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.94 mg/mL |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2805450 |
Product Specific Information
Immunogen sequence:
EVIPSQYSSP TTIATVMNLS KKIKKIGVVV GNCFGFVGNR MLNPYYNQAY FLLEEGSKPE EVDQVLEEFG FKMGPFRVSD LAGLDVGWKS RKGQGLTGPT LLPGTPARKR GNRRYCPIPD VLCELGRFGQ KTGKGWYQYD KPLGRIHKPD PWLSKFLSRY RKTHHIEPRT ISQDEILERC LYSLINEAFR ILGEGIAASP EHIDVVYLHG YGWPRHKGGP MFYASTVGLP TVLEKLQKYY RQNPDIPQLE PSDYLKKLAS QGNPPLKEWQ SLAGSPSSKL
Positive Samples: HepG2, Mouse liver, Rat liver, Rat kidney
Cellular Location: Peroxisome
Target Information
EHHADH (enoyl-CoA-hydratase:3-hydroxyacyl-CoA dehydrogenase), also known as Peroxisomal L-bifunctional enzyme, is a 723 amino acid protein with an essential tripeptide sequence at its carboxyl terminus required for peroxisomal transport.
EHHADH-deficient mice exhibit a blunted peroxisome proliferative response when challenged with a peroxisome proliferator. Since there are no observed changes in lipid metabolism, enoyl-CoAs are thought to be diverted to the D-hydroxy-specific beta-oxidation system for metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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