Thermo Fisher Scientific MEP1B Polyclonal Antibody
Human MEP1B/Meprin beta 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot에 적합하며, 보존제가 없는 액상 형태. 단백질 A 및 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human MEP1B/Meprin beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788082 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human MEP1B/Meprin beta.
Target Information
Meprins are multidomain zinc metalloproteases highly expressed in mammalian kidney and intestinal brush border membranes, leukocytes, and certain cancer cells. They hydrolyze various peptide and protein substrates and are implicated in cancer and intestinal inflammation.
Mature meprins are oligomers of evolutionarily related alpha and/or beta subunits. Homooligomers of the alpha subunit are secreted, whereas oligomers containing the beta subunit are plasma membrane-bound.
This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression, and distribution of the membrane-associated alpha subunit in kidney and intestine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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