Thermo Fisher Scientific PCLO Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PCLO. Recombinant protein control fragment (Product #RP-90687). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PCLO,uniProtId:Q9Y6V0-5,ncbiNodeId:9606,antigenRange:3315-3450,antigenLength:5142,antigenImageFileName:PA5-53392_PCLO_Q9Y6V0-5_Rabbit.svg,antigenImageFileNamePDP:PA5-53392_PCLO_Q9Y6V0-5_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.30 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645284

Product Specific Information

Immunogen sequence: IYQYNYDPSG TASPQTTTEQ AILEGQYAAL EGSQFWATED ATTTASAVVA IEIPQSQGWY TVQSDGVTQY IAPPGILSTV SEIPLTDVVV KEEKQPKKRS SGAKVRGQYD DMGENMTDDP RSFKKIVDSG VQTDDE

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

Target Information

The protein encoded by the PCLO gene is part of the presynaptic cytoskeletal matrix, which is involved in establishing active synaptic zones and in synaptic vesicle trafficking. Variations in this gene have been associated with bipolar disorder and major depressive disorder. Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.