Thermo Fisher Scientific TMEM106B Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200

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Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Immunoprecipitation (IP)

Assay-dependent

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Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TMEM106B. Recombinant protein control fragment (Product #RP-100479). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TMEM106B,uniProtId:Q9NUM4-1,ncbiNodeId:9606,antigenRange:2-53,antigenLength:274,antigenImageFileName:PA5-63558_TMEM106B_Q9NUM4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63558_TMEM106B_Q9NUM4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648556

Product Specific Information

Immunogen sequence: GKSLSHLPLH SSKEDAYDGV TSENMRNGLV NSEVHNEDGR NGDVSQFPYV EF

Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 87%.

Target Information

Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.