Thermo Fisher Scientific Syntaxin 6 Recombinant Rabbit Monoclonal Antibody (821L4)

Applications

Western Blot (WB)

• Tested Dilution: 1–2 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Pig, Bovine, Rat, and Mouse.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity to diverse targets due to larger rabbit immune repertoire

Target Information

Syntaxin 6 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins involved in docking of synaptic vesicles with the presynaptic plasma membrane. They possess a single C-terminal transmembrane domain, a SNARE domain, and an N-terminal regulatory domain.

Syntaxins bind synaptotagmin in a calcium-dependent manner and interact with voltage-dependent calcium and potassium channels via the C-terminal H3 domain. They play a key role in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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