Thermo Fisher Scientific Histone H2B Polyclonal Antibody
Rabbit polyclonal antibody against human Histone H2B. Validated for WB and IHC(P). Detects endogenous HIST2H2BE. Supplied as liquid, 1 mg/mL in PBS with 50% glycerol. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HIST2H2BE, corresponding to a region within C-terminal amino acids. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899996 |
Product Specific Information
Antibody detects endogenous levels of total HIST2H2BE.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). These structures compact DNA into chromatin, limiting accessibility to cellular machinery that requires DNA as a template. Histones play central roles in transcription regulation, DNA repair, replication, and chromosomal stability. H2B also exhibits broad antibacterial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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