Thermo Fisher Scientific MSC Polyclonal Antibody
Thermo Fisher Scientific의 MSC 폴리클로날 항체는 인간 및 생쥐 MSC 단백질을 검출하는 연구용 항체입니다. Western blot과 IHC(P)에서 사용 가능하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal of human Musculin (UniProt ID: O60682-1, antigen range: 158–184) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635222 |
Product Specific Information
This antibody detects endogenous levels of total MSC protein.
Target Information
MyoD-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many muscle-specific terminal differentiation genes. MyoD complexes potently induce transcriptional activation, while musculin complexes bind adjacent to MyoD DNA-binding regions to repress MyoD activity, resulting in delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down-regulated during myogenesis and at the onset of terminal differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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