Thermo Fisher Scientific CSF2 Monoclonal Antibody (OTI8G5), TrueMAB
인간 CSF2(GM-CSF)에 특이적인 마우스 단클론 항체로, WB 및 IHC(P) 실험에 최적화됨. 고순도 친화 크로마토그래피 정제, 액상형 1 mg/mL 농도. 연구용으로만 사용 가능하며, 안정적인 PBS/BSA/glycerol 보존 용액 제공.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8G5 |
| Immunogen | Human recombinant protein fragment (aa 18–144 of human CSF2 produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in the chromosome region 5q31, associated with interstitial deletions in 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13.
The gene promotes tissue inflammation, and elevated cytokine levels, including GM-CSF, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome (ARDS). Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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