Thermo Fisher Scientific XPB Monoclonal Antibody (OTI6H8)
ERCC3(XPB) 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 IHC(Paraffin) 적용 가능. 고순도 Affinity Chromatography 정제, 1 mg/mL 농도, 안정적 PBS/BSA/glycerol buffer 구성. 연구용으로 DNA 수선 및 전사 인자 TFIIH 관련 분석에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6H8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 191–436 of ERCC3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723789 |
Target Information
The human XPB DNA helicase is a subunit of the DNA repair/basal transcription factor TFIIH and is involved in early steps of the nucleotide excision repair (NER) pathway. Mutations in the XPB gene can lead to clinical phenotypes such as xeroderma pigmentosum associated with Cockayne’s syndrome (XP/CS) and trichothiodystrophy (TTD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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