Thermo Fisher Scientific PHGDH Monoclonal Antibody (01)
인간 PHGDH 단백질에 특이적인 Mouse IgG2b 단클론 항체. ICC/IF 및 Flow Cytometry에 사용 가능. 보존제 무첨가 액상 형태로 제공되며, 단백질 A로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:20–1:100
Flow Cytometry (Flow)
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 01 |
| Immunogen | Recombinant Human PGDH/PHGDH protein (Met1–Phe533) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785337 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human PGDH/PHGDH.
Target Information
The PHGDH gene encodes an enzyme involved in the early steps of L-serine synthesis in animal cells.
L-serine is essential for D-serine and other amino acid synthesis.
The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity.
Mutations in this gene are associated with congenital microcephaly, psychomotor retardation, and other symptoms.
Multiple alternatively spliced transcript variants have been identified, though most full-length forms are not yet known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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