Thermo Fisher Scientific EB1 Polyclonal Antibody
EB1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), IP에 적합합니다. 미세소관 말단 결합 단백질 연구에 활용되며, 세포 극성 및 염색체 안정성 연구에 유용합니다. 액상 형태로 제공되며, 4°C 또는 -20°C에서 보관 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1–5 µL/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human MAPRE1 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2866910 |
Target Information
EB1 family proteins are evolutionarily conserved proteins that bind microtubule plus-ends and centrosomes, regulating microtubule dynamics and organization. The MAPRE genes encode EB1 family proteins—MAPRE1, MAPRE2, and MAPRE3—corresponding to EB1, RP1, and EBF3, respectively. EB1 (MAPRE1) gene, located at 20q11.2, can fuse to MLL in certain leukemia cases. EB1 interacts with the APC tumor-suppressor protein and plays crucial roles in microtubule regulation, cell polarity, and chromosome stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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