Thermo Fisher Scientific ACBD3 Monoclonal Antibody (OTI5F9), TrueMAB
ACBD3 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, Flow cytometry에 사용 가능. 인간 시료에 반응하며, 친화 크로마토그래피로 정제됨. 액상 형태로 -20°C에서 보관하며, 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F9 |
| Immunogen | Full length human recombinant protein of human ACBD3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
GOLPH1, also known as GCP60, was initially identified as a Golgi protein that interacts with the integral membrane protein giantin and is involved in maintaining Golgi structure. It also interacts with other Golgi proteins such as Golgin-160, which can be cleaved by caspases-2, -3, and -7, leading to nuclear localization of Golgin-160 fragments. The interaction between GOLPH1 and Golgin-160 fragments is regulated by the oxidation state of Cys-463 within GOLPH1. Additionally, GOLPH1 interacts with Numb, a cytosolic signaling protein that mediates asymmetric cell division of neural progenitor cells, suggesting a role in coupling cell fate determination with cell cycle progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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