Thermo Fisher Scientific Ku80 Polyclonal Antibody
Rabbit 유래 Ku80 폴리클로날 항체로 Western blot에 적합합니다. 인간, 생쥐, 햄스터, 랫트에 반응하며, 단백질 A로 정제된 액상 제품입니다. DNA 복구 관련 Ku80 단백질 연구용으로 사용됩니다.
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Applications
- Western Blot (WB): 1:500 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Hamster, Human, Mouse, Rat |
| Host / Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 323–338 (FSKVDEEQMKYKSEGK) of Ku80 conjugated to KLH at the C-terminus |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase and functions with the DNA ligase IV–XRCC4 complex in the repair of DNA double-strand breaks by non-homologous end joining and the completion of V(D)J recombination events. This gene complements Chinese hamster xrs-6 mutants defective in DNA repair and V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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