Thermo Fisher Scientific EPCAM Monoclonal Antibody (OTI2B8), TrueMAB
EpCAM 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western Blot, IHC, ICC/IF에 사용 가능. 인간 시료 반응성이 높으며, Lyophilized 형태로 제공. 연구용으로 세포 접착 및 암 관련 표지 연구에 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific EPCAM Monoclonal Antibody (OTI2B8), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B8 |
| Immunogen | Full-length human recombinant EPCAM protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Ep-CAM (epithelial adhesion molecule, ESA) is a transmembrane glycoprotein (~40 kDa) expressed in epithelial tissues. It mediates Ca²⁺-independent homotypic cell adhesion and influences cell cycle, proliferation, and metabolism by inducing genes such as c-myc, cyclin A, and cyclin E.
Ep-CAM adhesion negatively regulates cadherin-mediated adhesion, affecting epithelial cell differentiation and growth. Overexpression is associated with enhanced epithelial proliferation and is a marker for tumors of epithelial origin.
Ep-CAM is expressed on the baso-lateral surface of most simple epithelia and various carcinoma types, distinguishing adenocarcinomas from pleural mesotheliomas.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
제품 이미지
(이미지 파일은 본문 하단에 배치)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.