Thermo Fisher Scientific Cadherin 17/LI Cadherin (Liver-Intestine Marker) Monoclonal Antibody (CDH17/2616)
Cadherin 17 단백질을 인식하는 mouse monoclonal antibody로, 간 및 장 표지(marker) 연구용으로 적합합니다. IHC(P), IHC(PFA), Peptide Array에 사용 가능하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 단백질 A로 정제되었으며, PBS(pH 7.4) buffer에 보존제가 포함되어 있지 않습니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | - |
| Peptide Array (Array) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CDH17/2616 |
| Immunogen | Recombinant fragment (around aa 242–418) of human Cadherin 17 protein (CDH17) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CDH17 gene belongs to the cadherin superfamily, encoding calcium-dependent, membrane-associated glycoproteins.
This cadherin-like protein contains seven extracellular cadherin domains and a transmembrane region but lacks the conserved cytoplasmic domain.
It is expressed in the gastrointestinal tract and pancreatic ducts, functioning as an intestinal proton-dependent peptide transporter involved in the absorption of peptide-based drugs.
Additionally, it may play a role in the morphological organization of the liver and intestine.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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